Are Stretch Marks Inevitable When You Lose Weight? They’re not just a problem for women. Losing weight may boost your confidence and lower your chances of developing diabetes, but shedding extra pounds also has it’s drawbacks–like stretch marks. Essentially a scar, the marks develop when collagen and elastin, two proteins that keep skin healthy, are damaged. Losing weight slowly can lower your chances of developing stretch marks, says Dr. Nazanin Saedi, M.D., Director of the Jefferson Laser Surgery and Cosmetic Dermatology Center in Philadelphia, Penn. According to Dr. Konstantinos Spaniolas, associate director of the Bariatric and Metabolic Weight Loss Center at Stony Brook University, it’s best to lose no more than one percent of your body weight each week. This helps you retain muscle, weight loss, and yes, reduces the likelihood of getting stretch marks.